You can configure your f-keys with your F-Keys Manager. For the configuration of the f-keys I`ve made a list with some of the commands you can activate with the f-keys:

/ns (nickserv)

/cs (chanserv)

/ms (memoserv)

/NAlarm (alarm clock)

/cnl (nicklist colors)

/away (activate away mode)

/back (dezacticvate away mode)

/pxfk.fkeys (f-keys manager)

/mts (theme loader)

/ppmain (password protection)

/ppidle (idle protection)

/sbnc (BNC manager)

/scanner (scanner)

/quit (quit mirc)

/takeover.doz (takeover menu)

/cxcmd (X-Commands)

/mp3c (MP3 Player)

/cx.winamp (Winamp Control)  

I think that`s enough. :)